The proteins including enzymes purified with immobilized heparin have a long list, and some of them are listed below: mast cell proteases, lipoprotein lipase, coagulation enzymes, elastases, extracellular superoxide dismutase, serine protease inhibitors, such as AT3, heparin cofactor 2 and protease nexin, which inactivates serine proteases in the extracellular matrix. Other heparin binding proteins in the extracellular matrix are vitronectin, fibronectin, thrombospondin, laminin, collagen and Growth factors such as fibroblast growth factor (FGF), Schwann cell growth factor, retinal survival factor and homopoietic growth factor.
Specifications:
Particle Size (μm) | 50 |
Pore Size (Å) | 800 |
Ligand Density | about 5 mg/mL heparin of porcine origin |
Target Protein Binding Capacity (g/ml) | 2 mg antithrombin III |
Bead Matrix | Polyacrylate |
Recommended Flow Rate (cm/h) | 200-400 |
pH Stability | 4-13 |
Pressure (MPa) | 10 |
Chemical stability | 0.1 M NaOH (1 week at 20°C) 0.05 M sodium acetate 4 M NaCl, pH 4.0 8 M urea 6 M guanidine hydrochloride |
Storage buffer | 0.05 M sodium acetate containing 20% ethanol |
Storage temperature | +4–8 °C |
Ordering information: